Education

B.E. Vanderbilt University, Nashville, TN, 2017
   Majors: Biomedical Engineering, Mathematics

M.S., Biomedical Engineering, 2019, Columbia University

Awards

• Amgen Scholars Research Fellowship

• Tau Beta Pi

• NIH F31 Ruth L. Kirschstein Predoctoral Individual National Research Service Award

Areas of Research Interest

Cartilage tissue engineering, regenerative medicine, osteoarthritis, drug delivery

Background

Andy was first introduced to tissue engineering at Vanderbilt, where he worked with Dr. Hak-joon Sung to characterize the maturation of iPSC-derived cardiomyocytes using synthetic biomaterials. Through his work on the pathologies of the cardiovascular system, he developed an interest in disease characterization and reparative strategies at the cellular level. Andy first joined CEL at Columbia in the summer of 2015 and worked on a tissue engineered synovium model of inflammation in osteoarthritis progression. He came back in the fall of 2017 as a MS/PhD student and is now researching methods for sustained drug delivery in post-op joints to prevent arthrofibrosis. In his free time, Andy enjoys seeking out new cafes and eateries, and spends time outdoors playing tennis or running.

Selected Publications

1. Lee AJ, Mahoney CM, Cai CC, Ichinose R, Stefani RM, Marra KG, Ateshian GA, Shah RP, Vunjak-Novakovic G, Hung CT. Sustained delivery of SB-431542, a Type I TGF-β1 Receptor Inhibitor, to Prevent Arthrofibrosis. Tissue Engineering, Part A, in press (2021).

2. Stefani RM, Lee AJ, Tan AR, Roach BL, Durney KM, Halder SS, Stoker AM, Ateshian GA, Guo XE, Marra KG, Cook JL, Hung CT. Sustained low-dose dexamethasone delivery is chondroprotective and enhances clinical repair of cartilage legions. Acta Biomaterialia (2019) link

3. Estell EG, Silverstein AM, Stefani RM, Lee AJ, Murphy LA, Shah RP, Ateshian GA, Hung CT. Cartilage Wear Particles Induce an Inflammatory Response Similar to Cytokines in Human Fibroblast-Like Synoviocytes. J Orthop Res. 2019 May 7. doi: 10.1002/jor.24340. [Epub ahead of print] link

4. Stefani RM, Halder SS, Estell EG, Lee AJ, Silverstein AM, Sobczak E, Chahine NO, Ateshian GA, Shah RP, Hung CT. A Functional Tissue Engineered Synovium Model to Study Osteoarthritis Progression and Treatment. Tissue Eng Part A. 2018 Sep 11. doi: 10.1089/ten.TEA.2018.0142. [Epub ahead of print] link

5. Walsh AJ, Cook RS, Lee JH, Arteaga CL, Skala MC. Collagen density and alignment in responsive and resistant trastuzumab-treated breast cancer xenografts. J Biomed Opt. 20(2), 26004, International Society for Optics and Photonics (2015).

6. Chun YW, Voyles DE, Rath R, Hofmeister LH, Boire TC, Wilcox H, Lee JH, Bellan LM, Hong CC, Sung HJ. Differential responses of induced pluripotent stem cellderived cardiomyocytes to anisotropic strain depends on disease status. Journal of Biomechanics (2015).